Blog
Blog
Essays and notes on mathematics made tangible, drug development, and AI. Each one is headed by one of the Live Pieces — a WebGL artwork running as you read, and the only thing on this site that is decoration rather than a computed figure.
- 2026-08-26 The instrument, not the illustration essay
- 2026-08-24 Eight Papers, Seven Threads map
- 2026-08-21 Instruments — the shortlist process
Pre-AI Writings
Between 2017 and 2019 I wrote about drug development for paying subscribers under the pen name Second-Level Investing. Five of those pieces are here as I wrote them, each with a headnote that grades what I claimed against what happened.
- 2018-11-19 Marinus May Have Figured Out PCDH19: Implications For CDKL5, PPD & RSE pre-AI
- 2018-05-17 Gene Therapy – Between Hope And Hype pre-AI
- 2018-04-30 Analyzing The Plazomicin AdCom Briefing Documents pre-AI
- 2018-01-21 Utility And Limitations Of Pre-Clinical Research: The Example Of Genetic Epilepsies pre-AI
- 2017-12-03 Opportunity Cost, Limitations And Differentiation pre-AI
Live Pieces
Twelve artworks, each a single fragment shader — no video, no textures, no stored state. One of the six made for a dark ground heads each essay above; the gallery runs all twelve at full size.